Obsessive compulsive disorder in a patient with tuberous sclerosis and subependymal giant cell astrocytoma

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Obsessive compulsive disorder in a patient with tuberous sclerosis and subependymal giant cell astrocytoma

Tuberous sclerosis complex (TSC) is a multi-system disorder with autosomal dominant inheritance, which can affect the brain, heart, skin, kidneys, lungs, and retina. We present an obsessive-compulsive disorder patient, with classic dermatological findings and subependymal giant cell astrocytoma in TSC.

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[Subependymal giant cell astrocytoma (tuberous sclerosis)].

Two cases of tuberous sclerosis with subependymal giant cell astrocytoma are presented. This rare autosomal dominant disorder was also detected in family members of the patients who had never had any symptoms of cerebral involvement. Both patients underwent surgery because of signs of increased intracranial pressure.

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Rare subependymal giant-cell astrocytoma in a neonate with tuberous sclerosis.

The patient was a full-term 3-day-old male infant. From birth , he had been lethargic and had had seizures. CT showed a large left frontal horn and mass in the foramen of Monro with left unilateral hydrocephalus and both subependymal and parenchymal nodules. The tumor and these nodules were hyperdense on unenhanced CT scans, and contrast-enhanced scans showed mild enhancement (Figs. 1 A and 1 B...

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Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis

Objectives—Intraventricular astrocytomas (subependymal giant cell astrocytomas) of tuberous sclerosis have a poor prognosis due to the obstruction of CSF flow. The aim of this study was to determine whether they could be diVerentiated during childhood and at an early preclinical stage, from subependymal nodules without any growing potential. Methods—The first two MRIs of all children referred t...

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Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex.

The authors present a 21-year-old woman who has been receiving rapamycin for 5 months for bilateral subependymal giant cell astrocytomas. The patient was started at a dose of 0.2 mg/kg/day. Levels were maintained between 11 and 13 ng/mL. Magnetic resonance imaging of the brain 2(1/2) months after initiating rapamycin demonstrated a decrease in size of both astrocytomas (11 to 7.5 mm on the righ...

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ژورنال

عنوان ژورنال: Journal of Solid Tumors

سال: 2016

ISSN: 1925-4075,1925-4067

DOI: 10.5430/jst.v6n1p59